CD69 Antigen

The CD69 antigen is a 60 kDa disulfide-linked dimeric structure, known as activation inducer molecule (AIM). This structure contains two differentially glycosylated forms (33 and 27 kDa) of a single core protein, that are covalently associated. This activation antigen is one of the earliest appearing cell surface glycoproteins (before other activation antigens such as IL2-R) after T or B-lymphocyte activation but is absent in resting lymphocytes. It is also expressed by activated macrophages, NK cells and other cell types including neutrophils, eosinophils and platelets. Its expression in vitro can be induced by different factors such as PMA, PHA or CD3 monoclonal antibodies.


 Clone: TP1.55.3  Isotype: IgG2b Mouse

The CD69 antibody is useful in combination with CD4, CD8 and CD3 antibodies for T cell activation studies. The TP1.55.3 antibody immunoprecipitates the 60 kDa homodimer and both 27 kDa and 33 kDa subunits from activated peripheral blood lymphocytes under reduced and non-reduced conditions.
 

 

Explore Beckman Coulter CD69 Conjugated Antibodies

Part Number Product Name Status Clone Size List Price Buy
RUO
TP1.55.3
100 Tests

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ASR
TP1.55.3
1 mL

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ASR
TP1.55.3
1 mL

-

ASR
TP1.55.3
2 mL

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CE
TP1.55.3
100 Tests

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Product Line Specifications

Format Liquid
Specificity CD69
Form APC
Clone TP1.55.3
Isotype IgG2b Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced A80711

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


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