Helios Antigen

Helios belongs to the Ikaros transcription factor family. Members of this family are DNA binding proteins containing two-zinc finger N terminal domains and protein binding domain. Helios expression is restricted to the T lymphocytes lineage. Helios is suggested to play an important role in CD4+CD25+FoxP3+ regulatory cells. It has been shown that Helios up-regulates the expression of FoxP3 expression by binding to the FoxP3 promoter. Helios is a highly conserved transcription factor that has 97% sequence homology between human and mice.


 Clone: 22F6  Isotype: IgG Hamster

The clone 22F6 reacts with human and mouse Helios.
 

Choose a Helios Model

Especificaciones de la línea de productos

Format Liquid
Specificity Helios
Form Pacific Blue*
Clone 22F6
Isotype IgG Hamster
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced B49311

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